B-TPMF

• Description :

  B-TPMF is a selective inhibitor of the KCa2.1 channel, with an IC50 of 30 nM, and it has a competitive functional interaction with CM-TPMF[1].

• CAS Number :

  [477865-65-9]

• UNSPSC :

  12352005

• Target :

  Potassium Channel

• Related Pathways :

  Membrane Transporter/Ion Channel

• Field of Research :

  Cardiovascular Disease

• Smiles :

  CON/C=N/C1=NN2C(C(OC3=CC=C(C(C)(C)C)C=C3)C)=CC=NC2=N1

• Molecular Formula :

  C19H24N6O2

• Molecular Weight :

  368.43

• References & Citations :

  [1]Charlotte Hougaard, et al. Evidence for a common pharmacological interaction site on K (Ca) 2 channels providing both selective activation and selective inhibition of the human K (Ca) 2.1 subtype. Mol Pharmacol. 2012 Feb;81 (2) :210-9.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported