(-) -Mitorubrinic acid

• Description:

  (-) -Mitorubrinic acid (Mitorubrinic acid) is a polyketide. (-) -Mitorubrinic acid is synthesis by two non-reducing polyketide synthase (PKS) genes (pks12 and pks11) in a sequential manner. (-) -Mitorubrinic is a virulence factor of Penicillium marneffei by improving its intracellular survival in macrophages[1].

• Product Name Alternative:

  Mitorubrinic acid

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  Drug Derivative; Fungal

• Related Pathways:

  Anti-infection; Others

• Field of Research:

  Infection

• Smiles:

  O=C(O[C@]1(C)C(C2=COC(/C=C/C(O)=O)=CC2=CC1=O)=O)C3=C(C)C=C(O)C=C3O

• Molecular Formula:

  C21H16O9

• Molecular Weight:

  412.35

• Precautions:

  P261-P280-P302+P352

• References & Citations:

  [1]Woo PC, et al. First discovery of two polyketide synthase genes for mitorubrinic acid and mitorubrinol yellow pigment biosynthesis and implications in virulence of Penicillium marneffei. PLoS Negl Trop Dis. 2012;6 (10) :e1871.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [58958-07-9]