TXA497

CAT: 0804-HY-125533Size: 1 EachDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-125533Size:1 Each

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

TXA497 is a potent local topical bactericide. TXA497 exerts its bactericidal effect by interfering with the polymerization kinetics of the bacterial cell division protein FtsZ, rather than inhibiting it. TXA497 shows strong activity against various Staphylococcus aureus strains, including MRSA and MSSA, with an MIC value ranging from 1.0 to 2.0 μg/mL. TXA497 skin deposition is concentration-dependent in its formulation, consistent with Fick's first law. TXA497 has limited systemic permeability through the lipid pathway of the stratum corneum and is easily absorbed through this route. TXA497 can be used for research on topical bactericidal agents[1].

CAS Number

1404289-52-6

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

NC(NCC1=CC(C2=CC=C(C(C)(C)C)C=C2)=CC=C1)=N

Molecular Formula

C18H23N3

Molecular Weight

281.40

References & Citations

[1]Dorrani M, et al. TXA497 as a topical antibacterial agent: comparative antistaphylococcal, skin deposition, and skin permeation studies with mupirocin. Int J Pharm. 2014 Dec 10;476 (1-2) :199-204.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-153695-01	TXA707

TXA497

Related Products

Popular Products