Celikalim

CAT: 0804-HY-123641Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-123641Size:1 Each

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Description

Celikalim (Way 120491) is an antihypertensive agent. Celikalim lowers blood pressure through opening potassium channelsin vascular smooth muscle. Celikalim can inhibit white thrombus formation. Celikalim is a potent potassium opener in dog model. Celikalim can be studied in thrombosis-related research[1][2].

CAS Number

124916-54-7

Product Name Alternative

Way 120491

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Potassium Channel

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Smiles

O=C1N([C@H]2[C@H](O)C(C)(C)OC3=CC=C(OC(F)(F)F)C=C23)CC4=C1C=CC=C4

Molecular Formula

C20H18F3NO4

Molecular Weight

393.36

Precautions

P261-P280-P302+P352

References & Citations

[1]Patelunas-Hoffman, D. M., et al., (1994) . Analysis of the potassium channel openers celikalim, pinacidil and cromakalim in platelet models of thrombosis. Thrombosis research, 74 (5), 441-452. |[2]de Lorenzi F. G. (1994) . Celikalim (WAY-120491) increases K+ outward flux in dog and human airway smooth muscle. Pulmonary pharmacology, 7 (2), 129-135.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Celikalim

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