BN-81674

• Description:

  BN-81674 is a somatostatin analogue and a selective antagonist of the non-peptide human somatostatin sst3 receptor (Ki=0.92 nM) . In addition, BN-81674 reversed the inhibition of cyclic AMP accumulation induced by 1 nM somatostatin through the sst3 receptor with an IC50 value of 0.84 nM. BN-81674 can be used in cancer research[1].

• UNSPSC:

  12352005

• Target:

  Somatostatin Receptor

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  CCCCCC1(N[C@H](CC2=C1NC3=C2C=CC=C3)C4=NC=C(N4)C5=CC=CC=C5)CCCCC

• Molecular Formula:

  C30H38N4

• Molecular Weight:

  454.65

• References & Citations:

  [1]Poitout L, et al. Identification of potent non-peptide somatostatin antagonists with sst3 selectivity[J]. Journal of medicinal chemistry, 2001, 44 (18) : 2990-3000.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  SSTR3

• CAS Number:

  [252278-73-2]