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Mocetinostat (Standard)

CAT: 0804-HY-12164R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12164R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mocetinostat (Standard) is the analytical standard of Mocetinostat. This product is intended for research and analytical applications. Mocetinostat (MGCD0103) is a potent, orally active and isotype-selective HDAC (Class I/IV) inhibitor with IC50s of 0.15, 0.29, 1.66 and 0.59 μM for HDAC1, HDAC2, HDAC3 and HDAC11, respectively. Mocetinostat shows no inhibition on HDAC4, HDAC5, HDAC6, HDAC7, or HDAC8.
CAS Number
726169-73-9
UNSPSC
12352100
Target
Apoptosis; Autophagy; HDAC; Reference Standards
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage; Epigenetics; Others
Field of Research
Cancer
Smiles
O=C(C1=CC=C(C=C1)CNC2=NC=CC(C3=CC=CN=C3)=N2)NC4=CC=CC=C4N
Molecular Formula
C23H20N6O
Molecular Weight
396.45
References & Citations
[1]Fournel M, et al. MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo. Mol Cancer Ther. 2008 Apr;7 (4) :759-68.|[2]Cai J, et al. The Effect of MGCD0103 on CYP450 Isoforms Activity of Rats by Cocktail Method. Biomed Res Int. 2015;2015:517295.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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