Diclofop

• Description:

  Diclofop (Dichlorfop acid) is an acetyl-CoA carboxylase (ACC) inhibitor. Diclofop is also the major metabolite of the herbicide Diclofop-methyl (HY-136367) . Diclofop exhibits antimalarial activity with an IC50 of 210 μM against P. falciparum[1][2].

• Product Name Alternative:

  Dichlorfop acid; (±) -Diclofop

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  Drug Metabolite; Parasite

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Field of Research:

  Infection

• Smiles:

  O=C(C(C)OC1=CC=C(C=C1)OC2=CC=C(C=C2Cl)Cl)O

• Molecular Formula:

  C15H12Cl2O4

• Molecular Weight:

  327.16

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]Wiesner J, et al. The plastid-like organelle of apicomplexan parasites as drug target. Curr Pharm Des. 2008;14 (9) :855-71.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [40843-25-2]