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Hyocholic Acid (Standard)

CAT: 0804-HY-121238R-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-121238R-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Hyocholic Acid (Standard) is the analytical standard of Hyocholic Acid. This product is intended for research and analytical applications. Hyocholic Acid is a bile acid found in pig. Hyocholic Acid can also be found in urine samples from patients with cholestasis. Hyocholic Acid promotes GLP-1 secretion via activating TGR5 and inhibiting FXR in enteroendocrine cells. Hyocholic Acid is known for its exceptional resistance to type 2 diabetes [1][2][3].
CAS Number
547-75-1
UNSPSC
12352211
Target
FXR; G protein-coupled Bile Acid Receptor 1; Others; Reference Standards
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Smiles
C[C@@H]([C@]1(CC[C@]2([C@@]3([C@@H]([C@@H]([C@@]4(C[C@@H](CC[C@@]4([C@]3(CC[C@@]21C)[H])C)O)[H])O)O)[H])[H])[H])CCC(O)=O
Molecular Formula
C24H40O5
Molecular Weight
408.57
References & Citations
[1]Zheng X, et al. Hyocholic acid species as novel biomarkers for metabolic disorders. Nat Commun. 2021 Mar 5;12 (1) :1487. |[2]van Berge Henegouwen, et al. Sulphated and unsulphated bile acids in serum, bile, and urine of patients with cholestasis. Gut 17 (11), 861-869 (1976) . |[3]Xiaojiao Zheng, et al. Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism. Cell Metab. 2021 Apr 6;33 (4) :791-803.e7.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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