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Bevantolol-d7 (hydrochloride)

CAT: 0804-HY-121186SSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-121186SSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bevantolol-d7 hydrochloride is the deuterium labeled Bevantolol hydrochloride. Bevantolol hydrochloride is a selective β1 and α1-adrenergic receptor antagonist with pKi values of 7.83, 6.9 in rat cerebral cortex, respectively. Bevantolol hydrochloride is a potent Ca2+ antagonist[1][2].
UNSPSC
12352005
Target
Adrenergic Receptor; Calcium Channel; Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Metabolic Disease; Neurological Disease
Smiles
OC(CNCCC1=CC=C(C(OC)=C1)OC)COC2=C([2H])C([2H])=C([2H])C(C([2H])([2H])[2H])=C2[2H].Cl
Molecular Formula
C20H21D7ClNO4
Molecular Weight
388.94
References & Citations
[1]M Takita, et al. Selectivity of Bevantolol Hydrochloride Towards Alpha- And Beta-Adrenoceptor Subtypes in Rat Cerebral Cortex. Jpn J Pharmacol. 1992 Feb;58 (2) :193-6. |[2]Takahiro Horinouchi, et al. Different Changes of Plasma Membrane Beta-Adrenoceptors in Rat Heart After Chronic Administration of Propranolol, Atenolol and Bevantolol. Life Sci. 2007 Jul 12;81 (5) :399-404.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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