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Fexarene

CAT: 0804-HY-121110Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-121110Size:1 Each
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Description
Fexarene is a potent and selective nonsteroidal Farnesoid X Receptor (FXR) agonist with an EC50 of 36 nM. Fexarene can be used in studies of cholesterol and bile acid metabolism[1].
CAS Number
574013-68-6
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
FXR
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
O=C(/C=C/C1=CC=CC(N(CC2=CC=C(C=C2)/C=C/C3=CC=CC=C3)C(C4CCCCC4)=O)=C1)OC
Molecular Formula
C32H33NO3
Molecular Weight
479.61
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Nicolaou KC, et al. Discovery and optimization of non-steroidal FXR agonists from natural product-like libraries. Org Biomol Chem. 2003 Mar 21;1 (6) :908-20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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