Products for Research Use Only
RegisterLogin

AMG8163

CAT: 0804-HY-121080Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-121080Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
AMG8163 is an orally active antagonist for TRPV1. AMG8163 inhibits Capsaicin -induced flinch in rats models, and exhibits anti-hyperalgesia effects in multiple pain models[1].
CAS Number
659731-59-6
UNSPSC
12352005
Target
TRP Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C(NC1=CC(C(F)(F)F)=CC=C1C2=NC=NC(OC3=C4N=C(SC4=CC=C3)NC(C)=O)=C2)OC(C)(C)C
Molecular Formula
C25H22F3N5O4S
Molecular Weight
545.53
References & Citations
[1]Gavva NR, et al., Repeated administration of vanilloid receptor TRPV1 antagonists attenuates hyperthermia elicited by TRPV1 blockade. J Pharmacol Exp Ther. 2007 Oct;323 (1) :128-37.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P10736-01AMG133 peptide payload
HY-P10736A-01AMG133 peptide payload (TFA)

Alternative Products

CatalogName
T23723-01AMG8163

Popular Products