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GSK1331268

CAT: 0804-HY-120662Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120662Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK1331268 is a selective, orally active agonist for mGluR2 with a pEC50 of 6.9. GSK1331268 exhibits good blood-brain barrier penetration. GSK1331268 regulates glutamate signaling, and can be used in research of neurodegenerative and neuropsychiatric diseases[1].
CAS Number
1207197-70-3
UNSPSC
12352005
Target
MGluR
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
ClC1=CN=C(N2CCN(CC2)CC3=NC4=C(N3C)C=CC=C4)N=C1
Molecular Formula
C17H19ClN6
Molecular Weight
342.83
References & Citations
[1]D'Alessandro PL, et al., The identification of structurally novel, selective, orally bioavailable positive modulators of mGluR2. Bioorg Med Chem Lett. 2010 Jan 15;20 (2) :759-62.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T27449-01GSK1331268

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