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URB524

CAT: 0804-HY-116798Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-116798Size:1 Each
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Description
URB524 is an irreversible FAAH inhibitor of O-aryl amino acid esters. URB524 inhibits FAAH by aminoformylation of Ser241. URB524 exhibits analgesic, antidepressant, and anti anxiety activity[1].
CAS Number
546141-07-5
UNSPSC
12352005
Target
FAAH
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C(NC1CCCCC1)OC2=CC=CC(C3=CC=CC=C3)=C2
Molecular Formula
C19H21NO2
Molecular Weight
295.38
References & Citations
[1]Lodola A, et al. Identification of productive inhibitor binding orientation in fatty acid amide hydrolase (FAAH) by QM/MM mechanistic modelling. Chem Commun (Camb) . 2008 Jan 14; (2) :214-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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