Methoctramine

• Description :

  Methoctramine is a potent and cardioselectivity antagonist of M2 muscarinic receptor. Methoctramine can inhibit Muscarine (HY-121404) -induced bradycardia in vivo. Methoctramine can be used in the study of cardiovascular diseases[1].

• CAS Number :

  [104807-40-1]

• UNSPSC :

  12352005

• Target :

  MAChR

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Field of Research :

  Cardiovascular Disease

• Smiles :

  COC1=CC=CC=C1CNCCCCCCNCCCCCCCCNCCCCCCNCC2=CC=CC=C2OC

• Molecular Formula :

  C36H62N4O2

• Molecular Weight :

  582.90

• References & Citations :

  [1]Jaiswal N, et, al. Methoctramine, a cardioselective antagonist: muscarinic receptor mediating prostaglandin synthesis in isolated rabbit heart. Eur J Pharmacol. 1991 Jan 3;192 (1) :63-70.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported