CMP-SiaNAz (sodium)

CAT: 0804-HY-112944ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-112944ASize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CMP-SiaNAz (CMP-NeuNAz) sodium is a sialic acid nucleotide sugar derivative. CMP-SiaNAz sodium is integrated into the glycosidic chain through the action of STs in the Golgi apparatus, forming SiaNAz substances. CMP-SiaNAz sodium can serve as a substrate for bacterial-derived sialic acid transferases and is used for chemical enzymatic labeling and imaging of cell surface glycosides[1][2].
Product Name Alternative
CMP-NeuNAz (sodium)
UNSPSC
12352005
Target
Sialyltransferase
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
NC(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(O[C@@]3(C(O[Na])=O)C[C@H](O)[C@@H](NC(CN=[N+]=[N-])=O)[C@H]([C@H](O)[C@H](O)CO)O3)(O[Na])=O)O2)=NC1=O
Molecular Formula
C20H28N7Na2O16P
Molecular Weight
699.43
References & Citations
[1]Hong S, et al. Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification. Nat Commun. 2019 Apr 17;10 (1) :1799.|[2]Martinez-Duncker I, et al. Towards in vivo imaging of cancer sialylation. Int J Mol Imaging. 2011;2011:283497.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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