NVC-422

• Description:

  NVC-422 is a N-chlorotaurine analog, virucidal agent, antibacterial agent. NVC-422 exhibits virucidal activity against Ad5 by the oxidative inactivation of key viral proteins (fiber and hexon), leading to the loss of viral integrity and infectivity. NVC-422 is shown to be highly effective in killing all microbial strains tested, including antibiotic-resistant S. aureus and E. faecium. NVC-422 can be used in the research of adenoviral conjunctivitis[1][2].

• UNSPSC:

  12352211

• Target:

  Bacterial; Drug Derivative

• Related Pathways:

  Anti-infection; Others

• Field of Research:

  Infection

• Smiles:

  CC(C)(N(Cl)Cl)CS(=O)(O)=O

• Molecular Formula:

  C4H9Cl2NO3S

• Molecular Weight:

  222.09

• References & Citations:

  [1]Yoon J, et al. Virucidal mechanism of action of NVC-422, a novel antimicrobial drug for the treatment of adenoviral conjunctivitis. Antiviral Res. 2011 Dec;92 (3) :470-8.|[2]Wang L, et al. Chemical characterization and biological properties of NVC-422, a novel, stable N-chlorotaurine analog. Antimicrob Agents Chemother. 2011 Jun;55 (6) :2688-92.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [846056-87-9]