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NVC-422

CAT: 0804-HY-111311Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-111311Size:1 Each
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Description
NVC-422 is a N-chlorotaurine analog, virucidal agent, antibacterial agent. NVC-422 exhibits virucidal activity against Ad5 by the oxidative inactivation of key viral proteins (fiber and hexon), leading to the loss of viral integrity and infectivity. NVC-422 is shown to be highly effective in killing all microbial strains tested, including antibiotic-resistant S. aureus and E. faecium. NVC-422 can be used in the research of adenoviral conjunctivitis[1][2].
CAS Number
846056-87-9
UNSPSC
12352211
Target
Bacterial; Drug Derivative
Related Pathways
Anti-infection; Others
Field of Research
Infection
Smiles
CC(C)(N(Cl)Cl)CS(=O)(O)=O
Molecular Formula
C4H9Cl2NO3S
Molecular Weight
222.09
References & Citations
[1]Yoon J, et al. Virucidal mechanism of action of NVC-422, a novel antimicrobial drug for the treatment of adenoviral conjunctivitis. Antiviral Res. 2011 Dec;92 (3) :470-8.|[2]Wang L, et al. Chemical characterization and biological properties of NVC-422, a novel, stable N-chlorotaurine analog. Antimicrob Agents Chemother. 2011 Jun;55 (6) :2688-92.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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