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LY164846

CAT: 0804-HY-111127Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-111127Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LY164846 is an orally active cephalosporin. LY164846 is highly sensitive to Haemophilus influenzae (including Ampicillin -resistant strains) and Moraxella catarrhalis (with MIC90 ≤ 4 μg/mL). LY164846 is generally sensitive to Methicillin (HY-121544) -resistant Staphylococcus aureus and Streptococcus (except Enterococcus) (with MIC90: 0.25 - 8 μg/mL), and moderately sensitive to anaerobic bacteria. LY164846 has MBC/MIC ratio to Haemophilus influenzae of ≤ 2, showing bactericidal activity. LY164846 can be used for research on respiratory and skin infections[1][2].
CAS Number
92218-37-6
UNSPSC
12352005
Target
Antibiotic; Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(C(N12)=C(C)CS[C@]2([H])[C@H](NC([C@H](N)C3=CSC4=CC=CC=C43)=O)C1=O)O
Molecular Formula
C18H17N3O4S2
Molecular Weight
403.48
References & Citations
[1]Lauderdale BL, et al. In vitro activity of an orally administered cephalosporin, LY164846, against potentially pathogenic respiratory and dermal bacterial isolates. Antimicrob Agents Chemother. 1986 Apr;29 (4) :560-4. |[2]Jones RN, et al. LY164846 in vitro antimicrobial activity testing, including disk diffusion susceptibility tests using 30-microgram disks. Antimicrob Agents Chemother. 1986 Mar;29 (3) :530-4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
β-lactam

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