Bengamide B

CAT: 0804-HY-110151Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-110151Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Bengamide B is an inhibitor for NF-κB with an IC50 of 85 nM. Bengamide B inhibits LPS (HY-D1056) -induced expression of TNF-α, IL-6 and MCP-1, exhibits anti-inflammatory activity. Bengamide B exhibits antitumor efficacy (IC50 for HCT-116 is 2 nM) [1].
CAS Number
[104947-69-5]
UNSPSC
12352005
Target
Interleukin Related; NF-κB
Related Pathways
Immunology/Inflammation; NF-κB
Field of Research
Cancer
Smiles
CC(C)/C=C/[C@@H](O)[C@H](O)[C@@H](O)[C@@H](OC)C(N[C@H]1CC[C@H](OC(CCCCCCCCCCCCC)=O)CN(C)C1=O)=O
Molecular Formula
C32H58N2O8
Molecular Weight
598.81
References & Citations
[1]Johnson TA, et al., Myxobacteria versus sponge-derived alkaloids: the bengamide family identified as potent immune modulating agents by scrutiny of LC-MS/ELSD libraries. Bioorg Med Chem. 2012 Jul 15;20 (14) :4348-55.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P11337Scyptolin B
HY-N8507Tunicamycin B
HY-N8339Decatromicin B
HY-N5182Chymostatin B
HY-N5171Aselacin B
HY-N1961-01Ophiopogonin B
HY-N16622Phrymarolin B
HY-N16602(±) -Blephenanthrofuran B
HY-N16438Phomopsin B
HY-N16055Cochliomycin B

Alternative Products

CatalogName
MBS5785245-01Bengamide B
442238-01Bengamide B discontinued

Popular Products