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Ceclazepide

CAT: 0804-HY-109028Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-109028Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ceclazepide (TR2-A), a CCK2R antagonist, is an orally active Mycobacterium abscessus inhibitor. Ceclazepide inhibits acid secretion in rats. Ceclazepide effectively suppresses the growth of M. abscessus wild-type strain and multiple subspecies. Ceclazepide inhibits M. abscessus growth within macrophages without causing harm[1][2].
CAS Number
1801749-44-9
Product Name Alternative
TR2-A
UNSPSC
12352005
Target
Bacterial; Cholecystokinin Receptor
Related Pathways
Anti-infection; GPCR/G Protein; Neuronal Signaling
Field of Research
Infection; Cardiovascular Disease
Smiles
CC(OCC(C)(C)C(CN1C2=CC=CC=C2C(C3=CC=CC=N3)=N[C@H](C1=O)NC(NC4=CC(NC)=CC=C4)=O)=O)=O
Molecular Formula
C30H32N6O5
Molecular Weight
556.61
References & Citations
[1]K.L. Therese, et al. Ceclazepide as novel Mycobacterium abscessus inhibitor. bioRxiv. April 03, 2024.|[2]Chen D, et al. Neuroendocrine mechanism of gastric acid secretion: Historical perspectives and recent developments in physiology and pharmacology. J Neuroendocrinol. 2023 Nov;35 (11) :e13305.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19197937-01Ceclazepide

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