Products for Research Use Only
RegisterLogin

Pyrazoloacridine (Standard)

CAT: 0804-HY-108969R-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-108969R-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Pyrazoloacridine (Standard) is the analytical standard of Pyrazoloacridine. This product is intended for research and analytical applications. Pyrazoloacridine (NSC 366140), an intercalating agent with anti-cancer activity, inhibits the activity of topoisomerases 1 and 2. Pyrazoloacridine (NSC 366140) exhibits an IC50 of 1.25 μM in K562 myeloid leukemia cells for 24 h treatment[1][2].
CAS Number
99009-20-8
UNSPSC
12352100
Target
Apoptosis; Reference Standards; Topoisomerase
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Others
Field of Research
Cancer
Smiles
O=[N+](C1=CC=C2C3=C1NC4=CC=C(OC)C=C4C3=NN2CCCN(C)C)[O-]
Molecular Formula
C19H21N5O3
Molecular Weight
367.40
References & Citations
[1]J S Sebolt, et al. Pyrazoloacridines, a new class of anticancer agents with selectivity against solid tumors in vitro. Cancer Res. 1987 Aug 15;47 (16) :4299-304.|[2]A A Adjei, et al. Effect of pyrazoloacridine (NSC 366140) on DNA topoisomerases I and II. Clin Cancer Res. 1998 Mar;4 (3) :683-91.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-108969-01Pyrazoloacridine
HY-P2274RArgifin (Standard)
HY-N9362REmodinanthrone (Standard)
HY-N7948RIsomaltotetraose (Standard)
HY-N7640RDeoxylimonin (Standard)
HY-N7617RToralactone (Standard)
HY-N7541RAntrodin A (Standard)
HY-N6739RBeauvericin (Standard)
HY-N6687RCalcimycin (Standard)
HY-N3373RLoganetin (Standard)

Alternative Products

CatalogName
BA3038-25Pyrazoloacridine
abx098968-01Standard
ST-08004-02Ascorbic Acid Standard + Gallic Acid Standard + TROLOX Standard + BRS Electrolyte
RE21029ARAb Standard A (Standard 0) 20 ml
ST-80004-01Ascorbic Acid Standard + Gallic Acid Standard + TROLOX Standard for biological samples
BA1634-50Pleconaril (Standard)
BA5440-25Thonzylamine (Standard)
BA5196-10Abaloparatide (Standard)

Popular Products