Ondelopran

CAT: 0804-HY-107121Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-107121Size:1 Each

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Description

Ondelopran (LY 2196044) is a non-selective opioid receptor antagonist. Ondelopran inhibits the release of dopamine in the nucleus accumbens induced by alcohol, reduces the rewarding effect of alcohol consumption, and lowers the craving. Ondelopran can be used for alcohol use disorder (AUD) [1].

CAS Number

676501-25-0

Product Name Alternative

LY 2196044

UNSPSC

12352005

Target

Opioid Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

FC1=C(OC2=CC=C(C(N)=O)C=N2)C=CC(CNCCC3CCOCC3)=C1

Molecular Formula

C20H24FN3O3

Molecular Weight

373.42

References & Citations

[1]Fischler PV, et al. Off-label and investigational drugs in the treatment of alcohol use disorder: A critical review. Front Pharmacol. 2022 Oct 3;13:927703.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Isoform

δ Opioid Receptor/DOR; κ Opioid Receptor/KOR; μ Opioid Receptor/MOR

Ondelopran

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