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Pacrinolol

CAT: 0804-HY-106500Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106500Size:1 Each
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Description
Pacrinolol (HOE 224) is a selective and orally active beta1 adrenergic receptor blocker. Pacrinolol can inhibit Isoprenaline -induced positive inotropic effect and increased heart rate. Pacrinolol can be used for the research of cardiovascular disease[1].
CAS Number
65655-59-6
Product Name Alternative
HOE 224
UNSPSC
12352005
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Cardiovascular Disease
Smiles
COC1=C(C=C(CCNCC(O)COC2=CC=C(/C(C)=C/C#N)C=C2)C=C1)OC
Molecular Formula
C23H28N2O4
Molecular Weight
396.48
References & Citations
[1]Lindner E. L-3,4- (3-3,4-dimethoxyphenethylamino-2-hydroxypropoxy) -phenyl- crotonic acid nitrile.HCl (Hoe 224), a beta-blocking agent with high beta 1-selectivity. Arzneimittelforschung. 1984;34 (3) :270-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
β adrenergic receptor

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