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Taltrimide

CAT: 0804-HY-106469Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-106469Size:1 mg
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Description
Taltrimide (MY-117), a lipophilic derivative of Taurine , strongly inhibits the sodium-independent binding of Taurine to synaptic membranes of brain, the effects on the binding of GABA being less pronounced. Taltrimide exhibits definitive anticonvulsive effects in experimental epilepsy models[1][2][3].
CAS Number
81428-04-8
Product Name Alternative
MY-117
UNSPSC
12352005
Target
Drug Derivative
Related Pathways
Others
Field of Research
Neurological Disease
Purity
90.000000
Smiles
O=S(CCN(C(C1=C2C=CC=C1)=O)C2=O)(NC(C)C)=O
Molecular Formula
C13H16N2O4S
Molecular Weight
296.34
References & Citations
[1]Airaksinen EM, et, al. Biochemical and clinical studies on epileptic patients during two phase I trials with the novel anticonvulsant taltrimide. Epilepsy Res. 1987 Sep;1 (5) :308-11.|[2]Keränen T, et, al. Effects of taltrimide, an experimental taurine derivative, on photoconvulsive response in epileptic patients. Epilepsia. 1987 Mar-Apr;28 (2) :133-7.|[3]Kontro P, et, al. Effects of the anticonvulsant taurine derivative, taltrimide, on membrane transport and binding of GABA and taurine in the mouse cerebrum. Neuropharmacology. 1987 Jan;26 (1) :19-23.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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