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Chiglitazar (sodium)

CAT: 0804-HY-106266BSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106266BSize:1 Each
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Description
Chiglitazar (Carfloglitazar) is a PPARα/γ dual agonist, with EC50s of 1.2, 0.08, 1.7 μM for PPARα, PPARγ and PPARδ, respectively.
CAS Number
2390374-10-2
Product Name Alternative
Carfloglitazar (sodium)
UNSPSC
12352005
Target
PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Smiles
O=C(C1=CC=C(C=C1)F)C(C=CC=C2)=C2N[C@H](C(O[Na])=O)CC(C=C3)=CC=C3OCCN4C5=CC=CC=C5C6=CC=CC=C64
Molecular Formula
C36H28FN2NaO4
Molecular Weight
594.61
References & Citations
[1]Li PP, et al. The PPARalpha/gamma dual agonist chiglitazar improves insulin resistance and dyslipidemia in MSG obese rats. Br J Pharmacol. 2006 Jul;148 (5) :610-8.|[2]He BK, et al. In Vitro and In Vivo Characterizations of Chiglitazar, a Newly Identified PPAR Pan-Agonist. PPAR Res. 2012;2012:546548.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
PPARα; PPARβ/δ; PPARγ

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GTR19203826-01Chiglitazar
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A12701-50Chiglitazar 50mg
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A12701-1Chiglitazar 1mg

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