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Mexiprostil

CAT: 0804-HY-106074Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106074Size:1 Each
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Description
Mexiprostil (MDL 646) is an orally active gastric protectant, being a synthetic analogue of Prostaglandin E1. Mexiprostil exhibits significant inhibition of gastric acid secretion caused by Histamine (HY-B1204) and Bethanechol (HY-B0406) in rats, dogs, and cats. Mexiprostil can also inhibit the increase in gastric acid secretion caused by Pentagastrin (HY-A0261) in cats, while it does not have this effect in dogs and rats. Mexiprostil does not cause pregnancy termination. Mexiprostil can be used for research on gastric ulcers[1][2].
CAS Number
88980-20-5
Product Name Alternative
MDL 646
UNSPSC
12352211
Target
Drug Derivative
Related Pathways
Others
Field of Research
Inflammation/Immunology
Smiles
CCCCC(OC)(C)[C@H](O)/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)CCCCCCC(OC)=O
Molecular Formula
C23H40O6
Molecular Weight
412.56
References & Citations
[1]Müller P, et al. An alprostadil analogue and human gastric secretion. A double-blind placebo-controlled study of the effects of a capsule and tablet formulation. Arzneimittelforschung. 1989 Jul;39 (7) :809-11.|[2]Scarpignato C, et al. Action of MDL 646, a new synthetic prostaglandin, on gastric acid secretion of some experimental animals. Res Commun Chem Pathol Pharmacol. 1983 Feb;39 (2) :211-28.|[3]Galliani G, et al. Studies on the luteolytic activity of MDL-646, a new gastroprotective PGE1 analogue, in the hamster. Prostaglandins. 1984 Apr;27 (4) :583-90.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
412080-01(16R) -Mexiprostil

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