Products for Research Use Only
RegisterLogin

Etazolate

CAT: 0804-HY-106044Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-106044Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Etazolate (SQ 64442) is a α-secretase activator, selective PDE4 inhibitor, selective GABAA receptor modulator. Etazolate reduces IL-1β levels Etazolate exerts a dose-dependent anti-inflammatory and anti-œdematous effect accompanied by lasting memory improvement. Etazolate produces an antidepressant-like effect[1][2][3].
CAS Number
51022-77-6
Product Name Alternative
SQ 64442
UNSPSC
12352005
Target
GABA Receptor; Interleukin Related; Phosphodiesterase (PDE)
Related Pathways
Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
C/C(C)=N\NC1=C2C(N(CC)N=C2)=NC=C1C(OCC)=O
Molecular Formula
C14H19N5O2
Molecular Weight
289.33
References & Citations
[1]Siopi E, et al. Etazolate, an α-secretase activator, reduces neuroinflammation and offers persistent neuroprotection following traumatic brain injury in mice. Neuropharmacology. 2013 Apr;67:183-92. |[2]Jindal A, et al. Etazolate, a phosphodiesterase-4 enzyme inhibitor produces antidepressant-like effects by blocking the behavioral, biochemical, neurobiological deficits and histological abnormalities in hippocampus region caused by olfactory bulbectomy. Psychopharmacology (Berl) . 2015 Feb;232 (3) :623-37. |[3]Marcade M, et al. Etazolate, a neuroprotective drug linking GABA (A) receptor pharmacology to amyloid precursor protein processing. J Neurochem. 2008 Jul;106 (1) :392-404.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
IL-1; PDE4

Related Products

CatalogName
HY-12611-01Sergliflozin etabonate
HY-14945-01Remogliflozin etabonate
HY-17358-01Loteprednol Etabonate
HY-17358S1-01Loteprednol Etabonate-d3
HY-17358S-01Loteprednol Etabonate-d5
HY-17358R-01Loteprednol Etabonate (Standard)

Alternative Products

CatalogName
574687Etazolate
B6304-5.1Etazolate hydrochloride
MBS6061389-01Etazolate (SQ 20009)

Popular Products