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Piquindone

CAT: 0804-HY-105903Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-105903Size:1 Each
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Description
Piquindone (Ro 22-1319) is a potent antipsychotic agent. Piquindone binds to a D2 dopaminergic receptor subtype in a sodium-dependent manner. Piquindone can be used in the research of schizophrenia[1][2].
CAS Number
78541-97-6
Product Name Alternative
Ro 22-​1319
UNSPSC
12352005
Target
Dopamine Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
CCC1=C(C)NC(C[C@@]2([H])[C@@]3([H])CN(C)CC2)=C1C3=O
Molecular Formula
C15H22N2O
Molecular Weight
246.35
References & Citations
[1]Nakajima T, et al. [3H]Ro 22-1319 (piquindone) binds to the D2 dopaminergic receptor subtype in a sodium-dependent manner. Mol Pharmacol. 1984 Nov;26 (3) :430-8.|[2]Cohen JD, et al. The efficacy of piquindone, a new atypical neuroleptic, in the treatment of the positive and negative symptoms of schizophrenia. J Clin Psychopharmacol. 1987 Oct;7 (5) :324-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D2 Receptor

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