Tomoxiprole

• Description :

  Tomoxiprole (MDL 035) is a new analgesic antiinflammatory agent. Tomoxiprole selectively inhibits cyclooxygenase-2 (IC50 = 7 nM) [1][2].

• Product Name Alternative :

  MDL 035

• UNSPSC :

  12352005

• Target :

  COX

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology; Neurological Disease

• Smiles :

  CC(N1C2=CC=C(C=CC=C3)C3=C2N=C1C4=CC=C(OC)C=C4)C

• Molecular Formula :

  C21H20N2O

• Molecular Weight :

  316.40

• References & Citations :

  [1]Assandri A, et al. Pharmacokinetics and metabolism of tomoxiprole, a new analgesic antiinflammatory agent, in the rat. Eur J Drug Metab Pharmacokinet. 1985 Apr-Jun;10 (2) :161-70. |[2]West RE Jr, et al. Tomoxiprole selectively inhibits cyclooxygenase-2. Prostaglandins. 1997 Dec;54 (6) :891-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  COX-1; COX-2

• CAS Number :

  [76145-76-1]