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Metallibure

CAT: 0804-HY-105636Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-105636Size:1 Each
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Description
Methallibure (ICI 33828) is a dithiocarbamoylhydrazine derivative and gonadotropic function blocker. Methallibure can block the action of pituitary gonadotropins in teleost fishes and inhibit germ cell maturation. Methallibure does not affect the histological structure of the thyroid gland but reduces the nuclear volume of thyroid epithelial cells. Methallibure can be used in the research of endocrine diseases[1][2].
CAS Number
926-93-2
Product Name Alternative
ICI 33828; Methallibure
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Drug Derivative; GnRH Receptor
Related Pathways
GPCR/G Protein; Others
Field of Research
Endocrinology
Purity
90.000000
Smiles
CNC(NNC(NC(C=C)C)=S)=S
Molecular Formula
C7H14N4S2
Molecular Weight
218.34
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Hoar W S, et al. Inhibition of the pituitary gonadotropic activity of fishes by a dithiocarbamoylhydrazine derivative (ICI 33,828) . General and Comparative Endocrinology, 1967, 8 (1) : 101-109.|[2]Löw O, et al. Morphometrie an indokrinen Organen. II. Karyometrie an Schilddrüsen von Hunden und Schweinen nach Applikation von TURISYNCHRON und SUISYNCHRON [Morphometry of endocrine organs. 2. Karyometry of dog and swine thyroid glands following administration of TURISYNCHRON and SUISYNCHRON]. Arch Exp Veterinarmed. 1974;28 (5) :725-30. German.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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