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Perrimustine

CAT: 0804-HY-105433Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-105433Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Perrimustine is a cysteamine (CysA) derivative with potent antitumor activity. Perrimustine exhibits significant effect on B16 melanoma and metastasized melanoma cells by causing DNA damage. Perrimustine exhibits antitumor effects in mice bearing various cancers, including lung carcinoma, leukemia, lymphoma, melanoma, colon carcinoma, and glioma. Perrimustine can be used for cancer research, such as melanoma and leukemia[1][2].
CAS Number
96413-13-7
UNSPSC
12352211
Target
Drug Derivative
Related Pathways
Others
Field of Research
Cancer
Smiles
CS(CCNC(N(N=O)CCCl)=O)=O
Molecular Formula
C6H12ClN3O3S
Molecular Weight
241.70
References & Citations
[1]Kim-Triana B, et al. Phase I trial of Perrimustine, a new cysteamine (2-chloroethyl) nitrosourea: an intrapatient escalation scheme. Anticancer Drugs. 1992 Jun;3 (3) :225-31.|[2]Godeneche D, et al. DNA damage induced by a new 2-chloroethyl nitrosourea on malignant melanoma cells. Cancer Res. 1990 Sep 15;50 (18) :5898-903.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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