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Alnespirone

CAT: 0804-HY-10347Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-10347Size:1 Each
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Description
Alnespirone (S-20499) is a selective, orally active 5-HT1A receptor agonist (K0.5 = 0.2 nM) . Alnespirone shows antidepressant-like and anxiolytic effects[1].
CAS Number
138298-79-0
Product Name Alternative
S-20499
UNSPSC
12352005
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C(CC12CCCC1)N(CCCCN(CCC)[C@H]3CC(C(OC3)=CC=C4)=C4OC)C(C2)=O
Molecular Formula
C26H38N2O4
Molecular Weight
442.59
References & Citations
[1]Mac Sweeney CP, et al. Antidepressant-like effects of alnespirone (S 20499) in the learned helplessness test in rats. Eur J Pharmacol. 1998 Mar 19;345 (2) :133-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
5-HT1 Receptor

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