Linagliptin-d6

• Description:

  Linagliptin-d6 (BI 1356-d6) is deuterium labeled Linagliptin. Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM.

• Product Name Alternative:

  BI 1356-d6

• UNSPSC:

  12352005

• Target:

  Isotope-Labeled Compounds

• Related Pathways:

  Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Smiles:

  O=C1N(C2=C(C(N1CC3=NC(C([2H])([2H])[2H])=C4C=CC=CC4=N3)=O)N(CC#CC)C(N5CCC[C@@H](N)C5)=N2)C([2H])([2H])[2H]

• Molecular Formula:

  C25H22D6N8O2

• Molecular Weight:

  478.58

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported