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Ilacirnon (Standard)

CAT: 0804-HY-101713RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-101713RSize:1 Each
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Description
Ilacirnon (Standard) is the analytical standard of Ilacirnon. This product is intended for research and analytical applications. CCX140 (CCX140-B) is a potent CCR2 antagonist.
CAS Number
1100318-47-5
Product Name Alternative
CCX140 (Standard) ; CCX140-B (Standard)
UNSPSC
12352005
Target
CCR; Reference Standards
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Others
Field of Research
Metabolic Disease; Endocrinology
Smiles
FC(F)(F)C1=CC(S(=O)(NC2=CC(C)=CN=C2C(C3=NC=NC4=C3C=CN4)=O)=O)=CC=C1Cl
Molecular Formula
C20H13ClF3N5O3S
Molecular Weight
495.86
References & Citations
[1]Sullivan T, et al. CCR2 antagonist CCX140-B provides renal and glycemic benefits in diabetic transgenic human CCR2 knockin mice. Am J Physiol Renal Physiol. 2013 Nov 1;305 (9) :F1288-97.|[2]Sullivan TJ, et al. Experimental evidence for the use of CCR2 antagonists in the treatment of type 2 diabetes. Metabolism. 2013 Nov;62 (11) :1623-32.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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