IDRA 21 (Standard)
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IDRA 21 (Standard)
Description:
IDRA 21 (Standard) is the analytical standard of IDRA 21 (HY-101528) . This product is intended for research and analytical applications. IDRA 21 is a positive and orally active modulator of the AMPA receptor. IDRA 21 facilitates excitatory neurotransmission via GluR1/2 receptors. IDRA 21 has the potential for the research of cognitive/memory disorders, including those associated with aging[1].Target:
IGluR; Reference StandardsRelated Pathways:
Membrane Transporter/Ion Channel; Neuronal Signaling; OthersField of Research:
Neurological DiseaseSmiles:
CC(NC1=CC=C(Cl)C=C12)NS2(=O)=OMolecular Formula:
C8H9ClN2O2SMolecular Weight:
232.69References & Citations:
[1]Buccafusco JJ, et al. The effects of IDRA 21, a positive modulator of the AMPA receptor, on delayed matching performance by young and aged rhesus monkeys. Neuropharmacology. 2004 Jan;46 (1) :10-22. doi: 10.1016/j.neuropharm.2003.07.002.|[2]Yamada KA, et al. The diazoxide derivative IDRA 21 enhances ischemic hippocampal neuron injury. Ann Neurol. 1998 May;43 (5) :664-9.Shipping Conditions:
Room temperatureScientific Category:
Reference StandardsCAS Number:
[22503-72-6]
