HTS01037 (Standard)

• Description:

  HTS01037 (Standard) is the analytical standard of HTS01037 (HY-101503) . This product is intended for research and analytical applications. HTS01037 is an inhibitor of fatty acid binding; and a competitive antagonist of protein-protein interactions mediated by AFABP/aP2 with a Ki of 0.67 μM.

• Target:

  FABP; Reference Standards

• Related Pathways:

  Metabolic Enzyme/Protease; Others

• Field of Research:

  Metabolic Disease

• Smiles:

  O=C (C1=C (NC (/C=C/C (O) =O) =O) C=C (C2=CC=CS2) S1) OC

• Molecular Formula:

  C14H11NO5S2

• Molecular Weight:

  337.37

• References & Citations:

  [1]Hertzel AV, et al. Identification and characterization of a small molecule inhibitor of Fatty Acid binding proteins. J Med Chem. 2009 Oct 8;52 (19) :6024-31.|[2]Duffy CM, et al. Identification of a fatty acid binding protein4-UCP2 axis regulating microglial mediated neuroinflammation. Mol Cell Neurosci. 2017 Apr;80:52-57.|[3]Long EK, et al. Fatty acids induce leukotriene C4 synthesis in macrophages in a fatty acid binding protein-dependent manner. Biochim Biophys Acta. 2013 Jul;1831 (7) :1199-207.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  682741-29-3