CC-885 (Standard)

• Description:

  CC-885 (Standard) is the analytical standard of CC-885 (HY-101488) . This product is intended for research and analytical applications. CC-885 is a cereblon (CRBN) modulator with potent anti-tumour activity. CC-885 is also a known degrader of GSPT1, inhibiting protein translation.

• Target:

  Ligands for E3 Ligase; Molecular Glues; Reference Standards

• Related Pathways:

  Others; PROTAC

• Field of Research:

  Cancer

• Smiles:

  O=C(NCC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2)=O)C=C1)NC4=CC=C(C)C(Cl)=C4

• Molecular Formula:

  C22H21ClN4O4

• Molecular Weight:

  440.88

• References & Citations:

  [1]Mary E. Matyskiela, et al. A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase. Nature. 2016 Jul 14;535 (7611) :252-7.|[2]Jochem M, et al. Degradome analysis to identify direct protein substrates of small-molecule degraders[J]. bioRxiv, 2024: 2024.01. 28.577572.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [1010100-07-8]