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Evobrutinib (Standard)

CAT: 0804-HY-101215RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-101215RSize:1 Each
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Description
Evobrutinib (Standard) is the analytical standard of Evobrutinib. This product is intended for research and analytical applications. Evobrutinib (M2951) is an orally active, potent, highly selective and irreversibly covalent BTK inhibitor, with an IC50 of 8.9 nM. Evobrutinib (M2951) can be used for the research of autoimmune diseases[1].
CAS Number
1415823-73-2
Target
Btk; Reference Standards
Related Pathways
Others; Protein Tyrosine Kinase/RTK
Field of Research
Inflammation/Immunology; Cancer
Smiles
C=CC(N1CCC(CNC2=NC=NC(N)=C2C3=CC=C(OC4=CC=CC=C4)C=C3)CC1)=O
Molecular Formula
C25H27N5O2
Molecular Weight
429.51
References & Citations
[1]Caldwell R, et al. Discovery of Evobrutinib: An Oral, Potent and Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases. J Med Chem. 2019 Aug 1.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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B2379-25Evobrutinib
A16824-2Evobrutinib 2mg
A16824-50Evobrutinib 50mg
A16824-1Evobrutinib 1mg
A16824-500Evobrutinib 500mg
A16824-10Evobrutinib 10mg
A16824-100Evobrutinib 100mg

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