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SF2523 (Standard)

CAT: 0804-HY-101146RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-101146RSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SF2523 (Standard) is the analytical standard of SF2523. This product is intended for research and analytical applications. SF2523 is a highly selective and potent inhibitor of PI3K with IC50s of 34 nM, 158 nM, 9 nM, 241 nM and 280 nM for PI3Kα, PI3Kγ, DNA-PK, BRD4 and mTOR, respectively.
CAS Number
1174428-47-7
Target
DNA-PK; Epigenetic Reader Domain; PI3K; Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Others; PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
O=C1C=C(N2CCOCC2)OC3=C1SC=C3C4=CC=C(OCCO5)C5=C4
Molecular Formula
C19H17NO5S
Molecular Weight
371.41
References & Citations
[1]Carlino L, et al. Dual Kinase-Bromodomain Inhibitors in Anticancer Drug Discovery: A Structural andPharmacological Perspective. J Med Chem. 2016 Oct 27;59 (20) :9305-9320.|[2]Andrews FH, et al. Dual-activity PI3K-BRD4 inhibitor for the orthogonal inhibition of MYC to block tumor growth and metastasis. Proc Natl Acad Sci U S A. 2017 Feb 14;114 (7) :E1072-E1080.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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Alternative Products

CatalogName
BA3950-10SF2523
A20557-100SF2523 100mg
A20557-50SF2523 50mg
A20557-1SF2523 1mg
A20557-500SF2523 500mg
A20557-10SF2523 10mg
A20557-25SF2523 25mg

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