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Brensocatib (Standard)

CAT: 0804-HY-101056RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-101056RSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Brensocatib (Standard) is the analytical standard of Brensocatib. This product is intended for research and analytical applications. Brensocatib (AZD7986) is an oral dipeptidyl peptidase 1 (DPP1) inhibitor with pIC50s of 6.85, 7.6, 7.7, 7.8, and 7.8 in human, mouse, rat, dog and rabbit, respectively[1].
CAS Number
1802148-05-5
Target
Dipeptidyl Peptidase; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Inflammation/Immunology
Smiles
O=C([C@H]1OCCCNC1)N[C@H](C#N)CC2=CC=C(C3=CC=C(OC(N4C)=O)C4=C3)C=C2
Molecular Formula
C23H24N4O4
Molecular Weight
420.46
References & Citations
[1]Doyle K, et al. Discovery of Second Generation Reversible Covalent DPP1 Inhibitors Leading to an Oxazepane Amidoacetonitrile Based Clinical Candidate (AZD7986) . J Med Chem. 2016 Oct 27;59 (20) :9457-9472.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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