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GSK4028 (Standard)

CAT: 0804-HY-101027ARSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-101027ARSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK4028 (Standard) is the analytical standard of GSK4028. This product is intended for research and analytical applications. GSK4028 is the enantiomeric negative control of GSK4027, which is a PCAF/GCN5 bromodomain chemical probe, the pIC50 of GSK4028 is 4.9 in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay.
CAS Number
2079886-19-2
Target
Epigenetic Reader Domain; Histone Acetyltransferase; Reference Standards
Related Pathways
Epigenetics; Others
Field of Research
Cancer; Inflammation/Immunology
Smiles
BrC1=C(N[C@H]2C[C@@H](C3=CC=CC=C3)CN(C)C2)C=NN(C)C1=O
Molecular Formula
C17H21BrN4O
Molecular Weight
377.28
References & Citations
[1]Humphreys PG, et al. Discovery of a Potent, Cell Penetrant, and Selective p300/CBP-Associated Factor (PCAF) /General Control Nonderepressible 5 (GCN5) Bromodomain Chemical Probe. J Med Chem. 2017 Jan 26;60 (2) :695-709.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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