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JQEZ5 (Standard)

CAT: 0804-HY-100846RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-100846RSize:1 Each
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Description
JQEZ5 (Standard) is the analytical standard of JQEZ5. This product is intended for research and analytical applications. JQEZ5 is a potent and selective EZH2 lysine methyltransferase inhibitor. JQEZ5 SAM-competitively inhibits polycomb repressive complex 2 (PRC2) with an IC50 of 80 nM. JQEZ5 has anti-tumor effects[1].
CAS Number
1913252-04-6
Target
Histone Methyltransferase; Reference Standards
Related Pathways
Epigenetics; Others
Field of Research
Cancer
Smiles
CC(N1N=CC2=C(C(NCC3=C(C=C(NC3=O)C)CCC)=O)C=C(C4=CC=C(N=C4)N5CCN(C)CC5)N=C12)C
Molecular Formula
C30H38N8O2
Molecular Weight
542.68
References & Citations
[1]Zhang H, et al. Oncogenic Deregulation of EZH2 as an Opportunity for Targeted Therapy in Lung Cancer. Cancer Discov. 2016 Sep;6 (9) :1006-21.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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