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Fezagepras (Standard)

CAT: 0804-HY-100775ARSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-100775ARSize:1 Each
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Description
Fezagepras (Standard) is the analytical standard of Fezagepras. This product is intended for research and analytical applications. Fezagepras (Setogepram) acts as an orally active agonist for GPR40 and as an antagonist or inverse agonist for GPR84[1]. Fezagepras decreases renal, liver and pancreatic fibrosis[1][2]. Fezagepras exerts anti-fibrotic, anti-inflammatory and anti-proliferative actions[2].
CAS Number
1002101-19-0
Product Name Alternative
Setogepram (Standard) ; PBI-4050 (Standard)
UNSPSC
12352005
Target
Free Fatty Acid Receptor; GPR84; Reference Standards
Related Pathways
GPCR/G Protein; Others
Field of Research
Metabolic Disease; Inflammation/Immunology
Smiles
O=C(CC1=CC=CC(CCCCC)=C1)O
Molecular Formula
C13H18O2
Molecular Weight
206.28
References & Citations
[1]Li Y, et al. Fatty acid receptor modulator PBI-4050 inhibits kidney fibrosis and improves glycemic control. JCI Insight. 2018 May 17;3 (10) . pii: 120365.|[2]Grouix B, et al. PBI-4050 Reduces Stellate Cell Activation and Liver Fibrosis through Modulation of Intracellular ATP Levels and the Liver Kinase B1/AMP-Activated Protein Kinase/Mammalian Target of Rapamycin Pathway. J Pharmacol Exp Ther. 2018 Oct;367 (1) :71-81.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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