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YUKA1 (Standard)

CAT: 0804-HY-100764RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-100764RSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YUKA1 (Standard) is the analytical standard of YUKA1. This product is intended for research and analytical applications. YUKA1 is a potent and cell permeable Lysine demethylase 5A (KDM5A) inhibitor, with an IC50 of 2.66 μM. YUKA1 has less inhibitory active on KDM5C (IC50 = 7.12 μM) and is inactive on KDM5B, KDM6A or KDM6B. YUKA1 can increase H3K4me3 levels and inhibit cell proliferation. YUKA1 can be used for the research of cancer, such as lung and breast cancers[1].
CAS Number
708991-09-7
Target
Histone Demethylase; Reference Standards
Related Pathways
Epigenetics; Others
Field of Research
Cancer
Smiles
C=CCOC1=C(CNN2C(NN=C2)=S)C=CC=C1OC
Molecular Formula
C13H16N4O2S
Molecular Weight
292.36
References & Citations
[1]Gale M, et al. Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance. Oncotarget. 2016 Jun 28;7 (26) :39931-39944.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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