Products for Research Use Only
RegisterLogin

BMS453 (Standard)

CAT: 0804-HY-100608RSize: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-100608RSize:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
BMS453 (Standard) is the analytical standard of BMS453. This product is intended for research and analytical applications. BMS453 (BMS-189453), a synthetic retinoid, is a RARβ agonist and a RARα/RARγ antagonist. BMS453 inhibits breast cell growth predominantly through the induction of active TGFβ[1][2].
CAS Number
166977-43-1
Target
RAR/RXR; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
O=C(O)C1=CC=C(/C=C/C2=CC=C3C(C)(C)CC=C(C4=CC=CC=C4)C3=C2)C=C1
Molecular Formula
C27H24O2
Molecular Weight
380.48
References & Citations
[1]J Y Chen, et al. RAR-specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation. EMBO J. 1995 Mar 15;14 (6) :1187-97.|[2]L Yang, et al. The retinoic acid receptor antagonist, BMS453, inhibits normal breast cell growth by inducing active TGFbeta and causing cell cycle arrest. Oncogene. 2001 Nov 29;20 (55) :8025-35.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-100608-01BMS453
HY-P2274RArgifin (Standard)
HY-N9362REmodinanthrone (Standard)
HY-N7948RIsomaltotetraose (Standard)
HY-N7640RDeoxylimonin (Standard)
HY-N7617RToralactone (Standard)
HY-N7541RAntrodin A (Standard)
HY-N6739RBeauvericin (Standard)
HY-N6687RCalcimycin (Standard)
HY-N3373RLoganetin (Standard)

Alternative Products

CatalogName
MBS5773166BMS453
A22082-100BMS453 100mg
A22082-5BMS453 5mg
A22082-50BMS453 50mg
A22082-25BMS453 25mg
A22082-10BMS453 10mg
A22082-10mM-DBMS453 10mM * 1mL in DMSO
abx098967-01Standard
ST-08004-02Ascorbic Acid Standard + Gallic Acid Standard + TROLOX Standard + BRS Electrolyte
RE21029ARAb Standard A (Standard 0) 20 ml

Popular Products