Susalimod

CAT: 0804-HY-100485Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-100485Size:1 Each

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Description

Susalimod is an immunomodulating agent and Sulfasalazine analogue. Susalimod decreases LPS-induced TNF-alpha mouse serum levels[1][2].

CAS Number

149556-49-0

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Drug Derivative

Related Pathways

Others

Field of Research

Inflammation/Immunology

Smiles

O=C(O)C1=CC(C#CC2=CC=C(S(=O)(NC3=NC=CC=C3C)=O)C=C2)=CC=C1O

Molecular Formula

C21H16N2O5S

Molecular Weight

408.43

Precautions

P261-P280-P302+P352

References & Citations

[1]Gozzi P, et al. Pharmacokinetic-pharmacodynamic modeling of the immunomodulating agent susalimod and experimentally induced tumor necrosis factor-alpha levels in the mouse. J Pharmacol Exp Ther. 1999 Oct;291 (1) :199-203. |[2]Påhlman , et al. Extensive biliary excretion of the sulfasalazine analogue, susalimod, but different concentrations in the bile duct in various animal species correlating to species-specific hepatobiliary toxicity. Pharmacol Toxicol. 1999 Sep;85 (3) :123-9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Susalimod

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