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KCL22-s/RFP stable cell line

CAT: 1049-GTR15423608Size: 1 VialDry Ice: NoHazardous: No
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CAT#:1049-GTR15423608Size:1 Vial
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Description
KCL22-s/RFP cells are derived from human lymphoblast-like cell line KCL22-s by stably integration of a constitutive RFP stably expression construct. KCL22-s cells are a variant of the KCL22 cell line that is sensitive to imatinib, a tyrosine kinase inhibitor commonly used to treat chronic myeloid leukemia (CML) . Imatinib targets the BCR-ABL fusion protein, which is a key driver of CML. The paired KCL22-s and KCL22-r clones are useful cell line models of sensitivity and resistance to imatinib. KCL22-s/RFP cells stably express RFP, can be used for in vitro assays and in vivo imaging.

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