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Rabbit Polyclonal Antibody to CLOCK

CAT: 1725-P13772-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P13772-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. Alternative splicing results in multiple transcript variants.
Product Name Alternative
KAT13D; bHLHe8
Swiss Prot
O15516
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human CLOCK
Clonality
Polyclonal
Applications
IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
CLOCK

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Alternative Products

CatalogName
NBP1-88615Rabbit Polyclonal CLOCK Antibody
TA372926CLOCK Rabbit Polyclonal Antibody

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