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Rabbit Polyclonal Antibody to CTLA4

CAT: 1725-P10781-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P10781-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
Product Name Alternative
CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3
Swiss Prot
P16410
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human CTLA4
Clonality
Polyclonal
Applications
IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
CTLA4

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