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Rabbit Polyclonal Antibody to CDC45

CAT: 1725-P09463-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P09463-01Size:50 µL
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Description
The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.
Product Name Alternative
CDC45L; MGORS7; CDC45L2; PORC-PI-1
Swiss Prot
O75419
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Fusion protein of human CDC45
Clonality
Polyclonal
Applications
IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
CDC45

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