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Rabbit Polyclonal Antibody to DOK4

CAT: 1725-P07969-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P07969-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Docking protein 4 is a protein that in humans is encoded by the DOK4 gene. Dok-4 is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins. Expressed in a variety of tissues with highest expression in liver, heart, kidney and skeletal muscle, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation. Additionally, Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation. Overexpression of Dok-4 is associated with clear cell renal cell carcinoma, suggesting a role for Dok-4 in tumorigenesis.
Swiss Prot
Q8TEW6
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Fusion protein of human DOK4
Clonality
Polyclonal
Applications
IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
DOK4

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NBP2-33274Rabbit Polyclonal DOK4 Antibody
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